You do not need to know which one you want. Five sit here, on different tissue and different clocks.
Book a consultationAsk us which one it is
Anti-aging treatments address four mechanisms: muscle movement, lost volume, bone support and skin quality. Five treatments sit under those four, each on its own clock — 2 to 7 days for a neuromodulator, six weeks for a collagen stimulator. Most plans address two or three.
Most people arrive with one thing that bothers them and no idea where it belongs. Anti-aging is a category, not a treatment.
Five treatments, four mechanisms, none substituting for another. A neuromodulator quiets the nerve signal. Filler places volume and dissolves with hyaluronidase.


| Approach | What it changes | Onset | Typical duration | Reversible | FDA status for this use |
|---|---|---|---|---|---|
| Neuromodulators (Botox®, Dysport®, Jeuveau®) | Lines produced by muscle movement, mostly upper face | 2 to 7 days by product | 3 to 4 months | No, but it wears off on its own | Botox® Cosmetic on-label for glabellar, lateral canthal and forehead lines and for moderate to severe platysma prominence; Dysport® and Jeuveau® for glabellar lines only; masseter and lip off-label for all three |
| Hyaluronic acid filler (Juvéderm®, Restylane®) | Volume and structural support at a specific site | Same day | 6 to 18 months at most sites, longer with some midface products | Yes, dissolvable with hyaluronidase | On-label by product and area, including the temple for Juvéderm® Voluma® XC and the infraorbital hollow for Juvéderm® Volbella® XC; a gel without the indication for that site is off-label there |
| Collagen stimulator (Sculptra®) | Your own collagen, built gradually and diffusely | Brief injection-fluid fullness, then about 6 weeks; most change between months 3 and 6 | Up to about 2 years in the pivotal studies | No | On-label in immune-competent people for shallow to deep nasolabial fold contour deficiencies and other facial wrinkles, with cheek wrinkles added in 2023; full-face and body use are off-label |
| Microneedling and platelet-rich fibrin | Skin texture, pore appearance, early fine lines, scarring | 4 to 8 weeks after the series begins | Held with 1 to 2 maintenance sessions a year | Not applicable | Microneedling devices are FDA-cleared; adding platelet-rich fibrin is not a cleared indication |
| Deoxycholic acid (Kybella®) | A defined pocket of fat, typically under the chin | 4 to 6 weeks per session; label allows up to 6 sessions a month apart, most need 2 to 4 | Destroyed fat cells are not expected to return; later weight change still applies | No | On-label under the chin; every other area is off-label |
There is no winner here, only different behavior. A treatment page's figure governs. Ranges reflect product labeling and observation in practice rather than a single study.
Botox® (onabotulinumtoxinA), Dysport® (abobotulinumtoxinA), Jeuveau® (prabotulinumtoxinA) — Botox® Cosmetic is FDA-approved for the temporary improvement in the appearance of moderate to severe glabellar, lateral canthal and forehead lines, and moderate to severe platysma prominence, in adults. Dysport® and Jeuveau® are approved for glabellar lines only. Masseter and lip treatment are off-label for all three. Neck treatment is on-label only for the platysma prominence indication Botox® Cosmetic holds, and off-label otherwise. Onset is 2 to 7 days by product, and the effect typically lasts 3 to 4 months.
Juvéderm® and Restylane® (hyaluronic acid) — Reversible with hyaluronidase, the enzyme that breaks hyaluronic acid down. Approvals are product-specific rather than category-wide. Juvéderm® Voluma® XC carries a temple indication, and Juvéderm® Volbella® XC carries an infraorbital one. A gel without the indication for that site is off-label there, so the question is which product is used rather than whether the area itself is approved.
Sculptra® (poly-L-lactic acid) — FDA-approved in immune-competent people for correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles, with cheek wrinkles added in 2023. Full-face and body use are off-label. Labeling describes an average of three injection sessions and permits up to four, spaced 4 to 6 weeks apart. Fullness on the day of treatment is injection fluid and settles within days. No enzyme removes it, so it is not reversible.
Medical microneedling — Devices are FDA-cleared, not FDA-approved. Typically 3 to 4 sessions about four weeks apart.
Platelet-rich fibrin (autologous) — Your own blood, prepared on site. Not an FDA-cleared indication in this combination, and the published evidence varies by use.
Kybella® (deoxycholic acid) — FDA-approved for submental fullness in adults, and every other area is off-label. The label allows sessions at least one month apart, up to six; most patients have 2 to 4. Swelling was reported in about 87% of patients in the trials and lasts several days, more after the first session.
The provider takes a history and examines your face at rest and in motion.
Standard views at fixed distance, lighting and angle. Then the mechanism is named.
You take this home whether or not you book: sequence, products, counts, price.
Treatment comes later, staged rather than stacked. The two-week review is read against baseline photographs.

The provider takes a history and examines your face. Injection, where it is indicated, happens at a separate visit.
What works within a week wears off within months. What holds a year takes months to appear.



No, though Botox® is often part of it. Botox® addresses one mechanism — lines produced by muscle movement — and does nothing for lost volume or skin texture. Most plans use two or three.
Age is not what decides, and you are not behind. What decides is whether a mechanism is active: a line visible at rest, a shadow in flat light. Where nothing is active, sunscreen and a retinoid do more.
No. Everything on this page is dosed against anatomy rather than a laboratory value, so the assessment is a history, an examination and photographs. Bloodwork belongs with your primary care.
Some of it. Botox® Cosmetic is FDA-approved for the temporary improvement in the appearance of moderate to severe glabellar, lateral canthal and forehead lines, and moderate to severe platysma prominence, in adults. Sculptra® and individual hyaluronic acid fillers hold their own product-specific indications. Microneedling devices are FDA-cleared, not FDA-approved. The U.S. Food and Drug Administration reviews each indication separately, and off-label uses are named before you consent.
Only hyaluronic acid filler. It dissolves with hyaluronidase, the enzyme that breaks hyaluronic acid down. A neuromodulator is not reversed but wears off over 3 to 4 months. Sculptra® and Kybella® are neither.
Treatment costs vary with the plan. Contact the practice for current pricing, what is included, and any applicable booking terms.
No. Stopping returns you to your own trajectory rather than to something worse. Neuromodulators wear off over 3 to 4 months, and most hyaluronic acid filler can be dissolved with hyaluronidase.
Discomfort is brief: fine needles, topical numbing where it helps, lidocaine in many hyaluronic acid gels. A neuromodulator and filler in one visit is routine. Collagen stimulators and microneedling sit about two weeks apart.
No, and knowing that now spares you a course of injectables. Nothing here lifts tissue or removes skin, so where laxity dominates, added volume makes a face heavier. The referral is to a facial plastic or oculoplastic surgeon.
The consultation may conclude that treatment is not suitable. Ask about consultation fees when booking. Two findings account for most: skin quality rather than volume, or recent weight change, sleep or sun.
Boxed warning for botulinum toxin products: the effects of botulinum toxin may spread from the injection site hours to weeks after treatment and can cause life-threatening difficulty swallowing or breathing. Seek emergency care if either occurs.
This page is general information, not medical advice, and not a substitute for an in-person evaluation. Individual results vary, and nothing described here is a promise of a specific result.
Several uses on this page are off-label. Off-label prescribing is legal and common in medicine. The category a given prescription falls into is named before you consent.
Botox®, Juvéderm® and Kybella® are trademarks of Allergan; Dysport® of Ipsen; Jeuveau® of Evolus; Restylane® and Sculptra® of Galderma. Rouge Aesthetics is not affiliated with, sponsored by or endorsed by those companies, and names them only to identify products used in this practice.
Product labeling changes. Where this page and the current prescribing information disagree, the prescribing information governs.
Rouge Aesthetics · 101 Mill Street, Suite 210, Gahanna, OH 43230 · (614) 425-1633
Individual results vary. This website provides general information and does not replace an individual consultation.