Juvéderm® in Columbus, OH: five hyaluronic acid gels, 15 to 25 mg/mL, each cross-linked for a different depth and each FDA-approved for a named area in adults over 21. The area decides which one, not the name.
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Juvéderm® is a family of five cross-linked hyaluronic acid gels from Allergan Aesthetics, each matched to a depth. Concentration runs 15 to 25 mg/mL, and each gel is FDA-approved for named areas in adults over 21. Labeled duration is up to one year, or up to two years for Voluma® XC in the cheek.
One word, five products, all the same molecule. Juvéderm® is Allergan Aesthetics' family of hyaluronic acid fillers, approved by the FDA as Class III medical devices under premarket approval rather than as drugs. Cross-linking stitches loose strands into a stable gel that holds its shape for months. Concentration across the family runs 15 to 25 mg/mL, and labeled duration is up to one year, or up to two years for Juvéderm® Voluma® XC in the cheek.
The area picks the gel, not the other way round. Cross-linking sets how a gel resists being flattened, which injectors call G prime. A high-G-prime gel holds a projection; a lower one blends.
| Product | HA concentration | Gel behavior | FDA-approved area (adults over 21) | Typical labeled duration |
|---|---|---|---|---|
| Juvéderm® Ultra XC | 24 mg/mL | Hylacross™. Soft and cohesive, holds water, spreads readily | Lip augmentation and perioral lines, plus moderate to severe facial wrinkles and folds such as nasolabial folds | Up to 1 year |
| Juvéderm® Ultra Plus XC | 24 mg/mL, more heavily cross-linked | Hylacross™. Denser than Ultra XC, placed deeper for volume beneath a fold | Moderate to severe facial wrinkles and folds such as nasolabial folds. Not approved for lip augmentation | Up to 1 year |
| Juvéderm® Volbella® XC | 15 mg/mL | VYCROSS®. Lowest concentration in the family, takes up less water and swells less. Placement depth is set by region. | Lip augmentation and perioral lines, plus correction of infraorbital hollowing | Up to 1 year |
| Juvéderm® Voluma® XC | 20 mg/mL | VYCROSS®. High lift capacity, placed deep and usually against bone | Cheek augmentation for age-related midface volume deficit, chin augmentation for chin retrusion, and temple hollowing | Up to 2 years in the cheek, up to 1 year in the chin |
| Juvéderm® Volux® XC | 25 mg/mL | VYCROSS®. Firmest in the family, highest resistance to deformation | Improvement of jawline definition | Up to 1 year |
What is in each syringe, how the gel behaves, the area it is FDA-approved for, and how long the label supports it. Indications and durations are taken from current U.S. product labeling for adults over 21. Individual duration varies.
Juvéderm® Ultra XC — 24 mg/mL Hylacross™ gel. Softer and more hydrophilic than the VYCROSS® products, so it swells more in the first 48 hours. Used when a lip needs body rather than border definition. Covered in depth on the lip filler page.
Juvéderm® Ultra Plus XC — Same 24 mg/mL concentration as Ultra XC with heavier cross-linking, placed deeper. It is approved for wrinkles and folds, not for lip augmentation. A fold is more often treated at the cheek that produced it than in the crease, which the smile lines page covers.
Juvéderm® Volbella® XC — 15 mg/mL VYCROSS® gel, the lowest concentration in the collection. Low swelling and smooth spread make it the choice for thin skin. FDA-approved for correction of infraorbital hollowing, an area most fillers are used in off-label, and placed deep there rather than superficially. See the under-eye page.
Juvéderm® Voluma® XC — 20 mg/mL VYCROSS® gel with high lift capacity, placed deep and usually on bone. FDA-approved for cheek augmentation, chin augmentation to improve chin retrusion, and temple hollowing, in adults over 21. Labeled up to 2 years in the cheek, the longest duration in the family. See the cheek and chin pages.
Juvéderm® Volux® XC — 25 mg/mL VYCROSS® gel, the firmest in the collection. Defines a border that already exists rather than creating skeletal projection. Jawline work typically takes 2 to 4 mL. See the jawline page.
Nothing is marked until photographs are taken. Bone, fat, skin and asymmetry are read at rest and moving.
You see the numbers before anything is opened: product, plane, syringe count and cost, written down.
Topical anesthetic first, then needle or cannula. Product goes in slowly, each side compared against the other.
By two weeks swelling has resolved. Photographs are repeated, and anything further is added then.
Topical anesthetic sits for 20 minutes, and every XC gel carries 0.3% lidocaine, so later passes are easier.
Give it two weeks before you judge it. Labeled duration runs up to one year for Ultra XC, Ultra Plus XC, Volbella® XC and Volux® XC, and up to two years for Voluma® XC in the cheek. Most patients sit inside the labeled range rather than at the top of it. Movement shortens it: a lip fades faster than a cheek on bone.
Both are hyaluronic acid; the difference is manufacturing. Juvéderm® gels are smooth and cohesive, spreading evenly into a rounded shape. Restylane® runs two lines: one firmer, one flexible. Neither outperforms the other.
Labeled duration is up to one year for Juvéderm® Ultra XC, Ultra Plus XC, Volbella XC and Volux XC, and up to two years for Voluma XC in the cheek. Most patients land inside those ranges rather than at the top. Enzymes in the tissue break the gel down, and movement speeds that up, so a lip fades faster than a cheek on bone.
Two of the five. Juvéderm® Ultra XC and Volbella XC are the two products in the family FDA-approved for lip augmentation in adults over 21. Volbella XC is 15 mg/mL and adds definition with less swelling; Ultra XC is 24 mg/mL and adds body. Most first-time lips take 0.5 to 1 mL.
Yes. Every product in the family is hyaluronic acid, so hyaluronidase breaks it down at any point, most of it within 24 to 48 hours. It is not selective: it reaches some of your own too, and a dense area sometimes needs a second session.
Filler moves when too much is placed, when the plane is wrong, or when a syringe is stacked too soon. The lip shows it as a shelf above the vermilion border. A two-week gap limits it.
Juvéderm® is priced per syringe, and the price differs by product. Current per-syringe pricing sits on the pricing page with a last-updated date. Most single-area plans use one to two syringes, and jawline work two to four.
Usually one or two, often across two visits. Most single areas take one to two syringes, and a jawline two to four. Lips are the exception, where 0.5 to 1 mL suits most first-timers.
Most patients describe pressure rather than pain. Topical anesthetic sits for 20 minutes, and every XC gel carries 0.3% lidocaine. Lips and the under-eye are most sensitive; a dental block is available for lip work.
Yes. Juvéderm® Volbella® XC is FDA-approved for correction of infraorbital hollowing in adults over 21, which makes it one of the few fillers approved for that area rather than used off-label there. It is placed deep, on or near bone, because the skin there is thin and a shallow gel shows through. Fluid retention and lid laxity change the answer.
Ask about follow-up timing, contact arrangements, and any additional charges before treatment.
Juvéderm®, VYCROSS® and Hylacross™ are trademarks of Allergan Aesthetics, an AbbVie company. Restylane® and Sculptra® are trademarks of Galderma. Rouge Aesthetics is not affiliated with, endorsed by or sponsored by either company, and names their products only to describe what is used here.
Indications and durations on this page are taken from current U.S. product labeling for adults over 21. Individual results vary, no result is promised, and this page is general information rather than medical advice.
Results vary between patients.
Signs of vascular compromise, including blanching, mottled or dusky skin, escalating pain or any change in vision, are emergencies. Call the practice immediately and seek emergency care for any visual change.
Treatment requires an in-person consultation and a medical eligibility review, and proceeds only where it is indicated.
Rouge Aesthetics · 101 Mill Street, Suite 210, Gahanna, OH 43230 · (614) 425-1633
Individual results vary. This website provides general information and does not replace an individual consultation.